The death was confirmed Sunday by Jackson's wife, Patricia. She says her husband died of cancer at the couple's home in Compton, Md. He was 76.
Jackson presided over a closely watched antitrust trial that resulted in his 2000 order that Microsoft be broken into two companies. An appeals court reversed the breakup order and appointed a different judge to determine a new punishment.
Jackson also presided over the drug possession trial of then-District of Columbia Mayor Marion Barry. Barry unsuccessfully appealed his six-month sentence, arguing that Jackson had shown bias in comments made to a Harvard University audience after his trial.